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Treatments > Medications Used In MS

Brand Name Chemical Name


terazosin (ter-AY-zoe-sin)

Primary Usage in MS

Generic Available
Bladder Dysfunction No

Terazosin belongs to the general class of medicines called anti-hypertensives, which are used to treat high blood pressure. It also helps relax the muscles of the prostate and the bladder. In MS, it is used to help promote the flow of urine through the sphincter.

Proper Usage
Use only as directed by your physician.

Terazosin may cause you to feel dizzy, lightheaded, or faint, especially when you get up from a sitting or lying position. While these effects are most likely to occur after the initial dose, they can happen at any time. You can reduce this problem by taking the medication at bedtime, but take special care if you need to get up in the middle of the night.

Dizziness, lightheadedness, or fainting are more likely to occur if you drink alcohol, stand for too long, or become overheated.

Terazosin can cause you to feel drowsy or less alert. Make sure you know how you react to this medication before driving.

Elderly individuals tend to be more sensitive to the effects of terazosin, and are therefore more likely to experience dizziness, lightheadedness, or fainting.

Studies have not been done in humans. In animal studies using terazosin at doses many times higher than those used in humans, no birth defects have been found. A decrease in successful pregnancies in these studies, however, has been found.

It is not known whether terazosin passes into the breast milk. Women who are taking this medication and wish to become pregnant should discuss it with their physician.

Be sure that your physician knows if you have any other medical problems, particularly angina (chest pain), severe heart disease, kidney disease.

Possible Side Effects
Side effects that typically go away as your body adjusts to the medication and do not require medical attention unless they continue for several weeks or are bothersome: headache; unusual tiredness or weakness; blurred vision; nausea.

Side effects that should be reported to your physician as soon as possible include: chest pain; dizziness or lightheadedness, especially when getting up from a lying or sitting position; fainting; pounding heartbeat; shortness of breath; swelling of feet or lower legs.

Medication Index

Other Medications Used to Treat Bladder Dysfunction

For Urination Frequency

Read more on bladder dysfunction and learn management strategies to help live comfortably.

Reprinted with permission from Rosalind C. Kalb (ed.), Multiple Sclerosis: The Questions You Have—The Answers You Need (4th ed.). New York: Demos Medical Publishing, 2007.

Last updated September 19, 2007