|Treatments > Medications Used In MS|
This medication causes dryness of the mouth. Because continuing dryness of the mouth can increase the risk of dental disease, alert your dentist if you are taking imipramine.
Imipramine may cause your skin to be more sensitive to sunlight than it is normally. Even brief exposure to sunlight may cause a skin rash, itching, redness or other discoloration of the skin, or severe sunburn. Stay out of the sun during the midday hours. Wear protective clothing and a sun block that has a skin protection factor (SPF) of at least 15.
This medication may affect blood sugar levels of diabetic individuals. If you notice a change in the results of your blood or urine sugar tests, check with your physician.
Do not stop taking imipramine without consulting your physician. The physician may want you to reduce the amount you are taking gradually in order to reduce the possibility of withdrawal symptoms such as headache, nausea, and/or an overall feeling of discomfort.
Studies of imipramine have not been done in pregnant women. There have been reports of newborns suffering from muscle spasms and heart, breathing, and urinary problems when their mothers had taken tricyclic antidepressants immediately before delivery. Studies in animals have indicated the possibility of unwanted effects in the fetus.
Imipramine passes into breast milk but has not been reported to have any effect on the nursing infant.
Possible Side Effects
Rare side effects that should be reported to your physician as soon as possible: anxiety; breast enlargement in males and females; hair loss; inappropriate secretion of milk in females; increased sensitivity to sunlight; irritability; muscle twitching; red or brownish spots on the skin; buzzing or other unexplained sounds in the ears; skin rash; itching; sore throat and fever; swelling of face and tongue; weakness*; yellow skin.
Symptoms of acute overdose: confusion; convulsions; severe drowsiness*; enlarged pupils; unusual heartbeat; fever; hallucinations; restlessness and agitation; shortness of breath; unusual tiredness or weakness*; vomiting.
* Since it may be difficult to distinguish between certain common symptoms of MS and some side effects of imipramine, be sure to consult your health care professional if an abrupt change of this type occurs.
|Last updated September 19, 2007|